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See also: • It is used to treat soft, brittle bones (). • It is used for bone growth. • It may be given to you for other reasons. Talk with the doctor. What do I need to tell my doctor BEFORE I take Denosumab Injection?

• If you have an allergy to or any other part of denosumab injection (). • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash;; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. • If you have low calcium levels. • If you are using another drug that has the same drug in it.

• If you are pregnant or may be pregnant. Do not take denosumab injection (prolia) if you are pregnant. • If you are breast-feeding or plan to breast-feed. This is not a list of all drugs or health problems that interact with denosumab injection (prolia).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, ) and health problems. You must check to make sure that it is safe for you to take denosumab injection (prolia) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Denosumab Injection? • Tell all of your health care providers that you take denosumab injection (prolia). This includes your doctors, nurses, pharmacists, and dentists. • This medicine may raise the chance of a. Talk with the doctor.

• After denosumab injection (prolia) is stopped, the chance of a broken bone is raised. This includes bones in the spine. The chance of having more than 1 broken bone in the spine is raised if you have ever had a broken bone in your spine. Do not stop treatment with denosumab injection (prolia) without talking to your doctor. • Have a as you have been told by your doctor. Talk with your doctor.

• Have blood work checked as you have been told by the doctor. Talk with the doctor. • Take calcium and as you were told by your doctor. • Have a before starting denosumab injection (prolia). • Take good care of your teeth. See a dentist often. • Very bad infections have been reported with use of denosumab injection (prolia).

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If you have any infection, are taking now or in the recent past, or have many infections, talk with your doctor. • This medicine may lower blood calcium levels. If you already have low blood calcium, it may get worse with denosumab injection (prolia).

Sometimes, blood calcium levels have stayed low for weeks or months after use of denosumab injection (prolia). Talk with the doctor. • This medicine is not approved for use in children. Talk with the doctor. • This medicine may cause harm to the unborn baby if you take it while you are pregnant. • If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting denosumab injection (prolia). Talk with your doctor.